Diagnostic value of the basophil activation test for sensitization to weed allergens
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چکیده
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The usefulness of the basophil activation test in monitoring specific immunotherapy with house dust mite allergens
Introduction In clinical practice, reliable tools for monitoring specific immunotherapy (SIT) are of utmost importance. Aim To assess the usefulness of the basophil activation test (BAT) in monitoring SIT in paediatric patients with allergy to house dust mites (HDM). Material and methods Thirty-one children qualified for SIT with HDM, of whom 21 completed the SIT during the observation peri...
متن کاملBasophil Activation Test Using Recombinant Allergens: Highly Specific Diagnostic Method Complementing Routine Tests in Wasp Venom Allergy
BACKGROUND Skin testing can expose allergic subjects to potential systemic reactions, sensitization against unrelated proteins, and increased risk of future sting reactions. Therefore the continuous improvement of in vitro diagnostic methods is desirable. Recombinant allergens have been shown to improve the sensitivity of specific IgE (sIgE) detection in vitro whilst no data is available regard...
متن کاملComparison of basophil activation test and lymphocyte transformation test as diagnostic assays for drug hypersensitivity
Lymphocyte transformation test (LTT) is a widely used assay to detect drug-specific T cell reaction, but its relatively low sensitivity renders risk for pseudo-negativity. Basophil activation test (BAT) is an emerging assay initially used to diagnose food allergy, but its application to drug hypersensitivity as been reported anecdotally. Although a promising assay, the clinical settings or a pa...
متن کاملbasophil activation test to optimize the diagnosis of adverse effects following immunization to vaccines.
adverse effects following immunization to vaccines (aefi) are considered extremely rare events, the occurrence of which could gain a major role in optimizing allergy diagnosis by cellular tests. the urgent need to eradicate infectious diseases from population, is the main goal of vaccination campaign, therefore its successful outcome should be almost undisputable. basophil activation test ...
متن کاملBasophil Activation Test for Chronic Urticaria
Dear Editor, Zehwan Kim et al, [1] presented a protocol to assay basophil activation by flow cytometry (FC) that included a phenotyping panel with CD123 and CD193 (CC chemokine receptor-3 [CCR3]). This method for the electronic capture of basophils in whole blood, never published before,raises some interesting questions. CCR3 (CD193), the eotaxin receptor, is commonly present in CD3-expressing ...
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ژورنال
عنوان ژورنال: Medical news of the North Caucasus
سال: 2020
ISSN: 2073-8137
DOI: 10.14300/mnnc.2020.15112